Pål Nyrén
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Pål Nyrén (born 1955[not verified in body]) was, as of June 2009, a biochemistry professor at the Royal Institute of Technology (KTH), Stockholm.[needs update][1][independent source needed] He is known for having developed the pyrosequencing method for DNA sequencing.[according to whom?][not verified in body]
Early life and education
[edit]This section may rely excessively on sources too closely associated with the subject, potentially preventing the article from being verifiable and neutral. (October 2025) |
Pål Nyrén was born 1955.[where?][citation needed] After undergraduate training,[clarification needed][where?] he received an M.S. in Chemical Engineering, in 1981, from the Royal Institute of Technology (KTH), in Stockholm, Sweden.[1][independent source needed] He then completed a Ph.D. in Biochemistry, at the University of Stockholm, in 1985,[1][independent source needed] with a dissertation entitled, "The Proton Pumping Pyrophosphatase From Rhodospirillum rubrum."[citation needed] He did a post-doctoral fellowship under John Walker[verification needed] at the MRC's Laboratory of Molecular Biology in Cambridge, England, from 1985-1986.[1][independent source needed]
Career
[edit]This section may rely excessively on sources too closely associated with the subject, potentially preventing the article from being verifiable and neutral. (October 2025) |
As Nyrén has stated at his faculty web page (as of June 2009),[needs update], he has held the following academic posts:
"1988 Associate professor (Docent) Biochemistry University of Stockholm"[;]
"1999 Professor in Biochemistry, KTH, Stockholm"[.][1][independent source needed]
He also lists himself as "[f]ounder of the company Biotage AB (former Pyrosequencing AB)" in 1997,[1][independent source needed] which is more accurately stated as his participating in the founding of a pyrosequencing unit, with other academics at KTH, a unit once a part of the complex set of businesses of Biotage AB created through mergers and acquisitions, with that pyrosequencing unit having been sold off to Qiagen in 2008.[2][3]
Recognition
[edit]In 2013, Nyrén was awarded the European Patent Office's European Inventor Award, in the SMEs category.[clarification needed][4]
Further reading
[edit]- Nyren, P.; Pettersson, B.; Uhlen, M. (1 January 1993). "Solid Phase DNA Minisequencing by an Enzymatic Luminometric Inorganic Pyrophosphate Detection Assay". Analytical Biochemistry. 208 (1): 171–175. doi:10.1006/abio.1993.1024. ISSN 0003-2697. PMID 8382019.
- Ronaghi, Mostafa; Uhlén, Mathias; Nyrén, Pål (17 July 1998). "A Sequencing Method Based on Real-Time Pyrophosphate". Science. 281 (5375): 363–365. doi:10.1126/science.281.5375.363. ISSN 0036-8075. PMID 9705713. S2CID 26331871.
References
[edit]- ^ a b c d e f Nyrén, Pål (23 January 2009). "Pål Nyrén". KTH Biotechnology, Division of Biochemistry (Biotech.KTH.se). Archived from the original (employment autobiography) on 29 June 2009. Retrieved 10 May 2010.[independent source needed]
- ^ In detail, Biotage AB actually arose, per its company description, from a series of events beginning with the 1969 founding by Colin Jones of Jones Chromatography (in Wales); the much later (1989) founding by Sheridan Snyder of Biotage LLC for "systems for drug discovery and purification" in the U.S.; the 1994 foundings of Argonaut Technologies by Larry Bock and Joel Martin in the U.S. and of Personal Chemistry (originally Labwell), in Stockholm, Sweden (a microwave synthesis startup), by Sharon Stone-Elander and Sören Nygren; the 1997 founding of Pyrosequencing AB, in Uppsala, Sweden, "specializing in developing instruments for sequencing DNA strands and building on technique developed at The Royal Institute of Technology, KTH, Stockholm" (with Stockholm IPO, 2000); the 2000 founding of MIP Technologies in Lund, Sweden by Christine Berggren and Kees Ensing; Argonaut's acquisition of Jones in 2002, Pyrosequencing's acquisitions of Biotage and Personal Chemistry in 2003, and the renaming of the conglomerate as Biotage AB at that time. Biotage AB went on to acquire Argonaut in 2005 and MIP in 2010, the latter only after, in 2008, having sold to Qiagen the "biosystems branch of Biotage AB and the Pyrosequencing brand" (the latter the unit possibly co-founded by title subject Pål Nyrén,[independent source needed] and Mostafa Ronaghi [in re: the latter, see Bornstein & Illumina (4 August 2008), op. cit.]). Note, see Biotage Staff (28 October 2025), op. cit.: the name "Pål Nyrén" does not appear on the Biotage AB history page, despite that page being rich with the names of founders of Biotage's component businesses.
- This historical summary is otherwise drawn entirely from Biotage Staff (28 October 2025). "Our History: Spanning Five Decades". Biotage.com. Retrieved 28 October 2025.
- ^ Bornstein, Maurissa & Illumina Staff (4 August 2008). "News Release: Illumina Appoints Mostafa Ronaghi as Senior Vice President and Chief Technology Officer". Illumina.com (Press release). San Diego, CA: Illumina, Inc. Archived from the original on 3 October 2008 – via Business Wire.
In 1997, [Mostafa Ronaghi] co-founded Pyrosequencing AB, which was later renamed to Biotage AB in 2003, and led the company to a successful initial public offering in June 2000 on the Stockholm Stock Exchange.
- ^ "Lighting up the code of life".